Benign Struma Ovarii; Malignant Struma Ovarii; Recent clinical studies. Struma Ovarii Struma Ovarii Nieminen, Usko; Numers, Claës; Widholm, Olof 1964-01-01 00:00:00 From the I Clinic (Professor Aarno Turunen, M.D.) Struma ovarii: CT findings. A careful examination for any thyroid microfollicles within fibrous septa or areas of solid stroma is key. Clinique: * The most frequently symptom is abdominal pain (50 %) though a high percentage (40 %) of patients were asymptomatic (1). Molecular analysis of tissues obtained from both the malignant struma ovarii and thyroid gland was performed. {"url":"/signup-modal-props.json?lang=us\u0026email="}, {"containerId":"expandableQuestionsContainer","displayRelatedArticles":true,"displayNextQuestion":true,"displaySkipQuestion":true,"articleId":14478,"mcqUrl":"https://radiopaedia.org/articles/struma-ovarii-tumour/questions/1892?lang=us"}. The vast majority of struma ovarii are benign tumours; however, malignant tumours of this type are found in a small percentage of cases. The tumor may present as a large abdominal mass, which can be palpable on examination depending upon size and location. Struma ovarii accounts for only 2 % of all mature teratomas, and less than 5 % of struma ovarii present malignant transformation [4, 6, 7]. Struma ovarii accounts for only 2 % of all mature teratomas, and less than 5 % of struma ovarii present malignant trans-formation [4, 6, 7]. 3. Clinical characteristics of struma ovarii. Magnetic resonance imaging findings may be more characteristic: The cystic spaces demonstrate both high and low signal intensity on T1- and T2-weighted images. Two months after the pelvic surgery, total thyroidectomy was performed, and a small nodule (0.8 cm) in the left lobe was diagnosed as a classical variant of PTC. A case report and review of the literature. First described by R Boettin in 1889 7,8. Owing to malignant struma ovarii (MSO) rarity, there has been some controversy about It is defined by the presence of thyroid tissue comprising more than 50% of the … Meigs JV. First described by Von Klden in 1895 and Gottschalk in 1899, struma ovarii is the most common type of monodermal teratoma, and comprises about 3.0% of all ovarian teratomas. Yoo SC, Chang KH, Lyu MO et-al. Struma ovarii accounts for approximately 5 percent of all ovarian teratomas [2-4]. Unable to process the form. Approximately 5-8% of cases can show symptoms or signs of thyrotoxicosis. Cysts derived from struma ovarii may mimic a mucinous or serous cystadenoma. Hatami M, Breining D, Owers RL et-al. Malignant struma ovarii is rarer still, On CT scans they are most often seen as smooth marginated multicystic masses with a high attenuation on precontrast scans and no or moderate cyst wall enhancement 4. Developed by renowned radiologists in each specialty, STATdx provides comprehensive decision support you can rely on - Struma Ovarii Struma ovarii is a teratoma in which thyroid tissue is present exclusively or forms a grossly recognizable component of a more complex teratoma [ 8 ]. Most MSO are histologically classified as papillary thyroid carcinomas (PTC). Scintigraphy showing increased radioiodine uptake in the pelvic mass compared to the thyroid is confirmatory. Thyroid tissue must comprise more than 50 percent of the overall tissue to be classified as a struma ovarii. Obstet. It represents 2–3% of all ovarian tumours and by definition must be comprised of at least half thyroid tissue [2–4]. Struma ovarii means ovarian goiter which originates from a single germ cell after the first meiotic division [1, 2] and is the most common type of mono- dermal teratoma in 3% of mature teratomas, 0.3-1% of ovarian tumour, 5-20% of mature teratoma has the component of thyroid tissue and only 2% of these cases were diagnos- ed SO. Invest. Radiographics. 6. Struma ovarii is rare; less than 200 cases have been reported in the medical literature [3, 5]. Struma ovarii is a monodermal germ cell tumor first de-scribed by R. Boëttlin in 1889 [1]. There is a slightly hyperechoic focus within the lesion which demonstrates post acoustic shadowing. Radiographics. struma ovarii and these can be corroborated by nuclear medicine. It is predominantly hypoechoic with internal septa and multiple thin echogenic bands. Struma ovarii is diagnosed when thyroid tissue comprises more than 50 % of the teratoma [4, 5]. We discuss the approaches leading to the correct diagnosis and we review the management of the disease. Patients may also experience expanding abdominal growth and a fluid wave consistent with ascites. In this article, a case of cystic struma ovarii with macrocystic change is presented. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Introduction: Struma ovarii accounts for 2% of mature teratomas. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. No fat is evident in these lesions. A clue to the diagnosis is the presence of a green to brown glairy fluid. In this study, we … Struma ovarii concurrently occurring with other ovarian epithelial tumors has been rarely reported. Struma ovarii is an uncommon type of teratomas, difficult to identify without histopathological examination. Patients may also experience expanding abdominal growth and a fluid wave consistent with ascites. By definition, at least 50% of the tumor mass must be represented by thyroid tissue (3). The rate of malignant transformation in struma ovarii is extremely low. * Pleural effusion and … The complications may include: Stress and anxiety due to fear of cancer of the ovary; Large tumor masses may get secondarily infected with bacteria or fungus; Hyperthyroidism: Presence of an overactive thyroid gland causing symptoms such as … Struma Ovarii. Boettlin R. Uber zahnentwickelung in dermoid cysten des ovariums. Struma ovarii is a rare type of mature teratoma, but its imaging features are rather distinct. Park SB, Kim JK, Kim KR et-al. It represents about 0.01% of overall ovarian tumours, and 5 to 10% of struma ovarii. Gynecol. ovarian teratomas with neural differentiation. CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. 7. PMID: 26149143. 2000;73 (865): 87-90. The ultrasound (US) features of struma ovarii are nonspecific, but a heterogeneous, predominantly solid mass may be seen. The gross pathologic appearance of struma ovarii differs from that of mature cystic teratomas where struma ovarii consist of amber-colored thyroid tissue, with hemorrhage, necrosis, and fibrosis. Etiology. Struma ovarii is diagnosed when thyroid tissue comprises more than 50 % of the teratoma [4, 5]. 4. Treatment is with surgical resection. Malignant struma ovarii--a case report and review of the literature. 2008;65 (2): 104-7. Oncogenic activation of BRAF (35% to 69%), RAS (10%), or RET (5% to 30%) is common in PTC, and the mutations correlate with tumor subtype, patient age, and clinical behavior. Struma ovarii occurs in patients with a substantially higher average age than for those with common mature teratomas. 2. Struma ovarii: management and follow-up … Imaging findings of complications and unusual manifestations of ovarian teratomas. 1. The mean age at diagnosis of MSO was 43 years old [ 6, 9 ]. We identified 10 such cases in our files. Despite its name, struma ovarii is not restricted to the ovary. Struma ovarii tumor is a subtype of an ovarian teratoma and is composed entirely or predominantly of thyroid tissue and containing variable-sized follicles with colloid material. Introduction. Struma ovarii is a rare cause of hyperthyroidism. Ce terme est réservé aux tératomes comportant de façon exclusive ou prédominante du tissu thyroïdien. 28 (4): 969-83. Although the preoperative suspicion of struma ovarii does not change the surgical attitude, it can modify and alert the clinician to the appropriate perioperative care of these patients, thereby diminishing their morbimortality. (1-6) It is defined as an ovarian teratoma that is composed predominantly of thyroid tissue (> 50%), or forms a … There is no internal vascularity. A struma ovarii (literally: goitre of the ovary) is a rare form of monodermal teratoma that contains mostly thyroid tissue, which may cause hyperthyroidism.[1]. They usually present a palpable abdominal mass and the tumors are unilateral and range from very small lesions up to as large as 10 cm in diameter. Histologic examination of tissues is a must to evaluate the extent of thyroid tissue in the teratoma, as well as for diagnostic purposes and differentiation from other types of ovarian tumors. It accounts for 0.3-1% of all ovarian tumors and ~3% of all mature cystic teratomas 1. The vast majority of struma ovarii are benign tumours; however, malignant tumours of this type are found in a small percentage of cases.[2]. Struma ovarii is a specialized or monodermal teratoma predominantly composed of mature thyroid tissue. Struma ovarii is a rare teratoma of the ovary that may contain functional thyroid follicular tissue, among others. May be seen as a multiloculated cystic mass, with solid parts. While imaging features can be non-specific and overlap with other ovarian neoplasms, ultrasound and CT usually demonstrate a complex adnexal lesion with multiple cystic and solid areas, reflecting the gross pathologic appearance of the tumor 1. Struma ovarii accounts for approximately 5 percent of all ovarian teratomas . Iodine-123 will be taken up by any functioning thyroid tissue, and is diagnostic of struma ovarii if seen in the adnexal region. Abstract. Struma ovarii is ectopic thyroid tissue associated with dermoid tumors or ovarian teratomas that can secrete excessive amounts of thyroid hormone and produce thyrotoxicosis. What are the possible Complications of Struma Ovarii? Virchows Arch Path Arat. Struma ovarii is diagnosed when thyroid tissue accounts for >50% of the teratoma. Gynecol. Struma ovarii tumor is a subtype of an ovarian teratoma and is composed entirely or predominantly of thyroid tissue and containing variable-sized follicles with colloid material. Discussion Le struma ovarii est un tératome mature monotissulaire rare. [3], "Ovarian teratomas: tumor types and imaging characteristics", https://en.wikipedia.org/w/index.php?title=Struma_ovarii&oldid=986132365, Creative Commons Attribution-ShareAlike License, This page was last edited on 30 October 2020, at 00:14. Struma ovarii is a rare ovarian tumour that has been reported to represent 0.5%–1.0% of all ovarian tumours. 22 (6): 1305-25. Check for errors and try again. Qian Y, Xiao Y, Zhen-Zhen L, Yu-Xin J, Jian-Chu LI, Na SU, Bo C, Bo Z Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2015 Jun;37(3):309-14. doi: 10.3881/j.issn.1000-503X.2015.03.012. To brown glairy fluid ovary that may contain functional thyroid follicular tissue, among others represents 2–3 % the. 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